msmsTests package LC-MS/MS post test filters to improve reproducibility
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چکیده
منابع مشابه
Reproducibility assessment of relative quantitation strategies for LC-MS based proteomics.
The reproducibility of a given method for relative quantitation governs the reliability of liquid chromatography-mass spectrometry (LC-MS) based differential analysis in proteomic studies. Understanding the noise level introduced from biological, chemical, and instrumental sources not only helps to determine the experimental design but also aids in assessing the reliability of expression ratios...
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Liquid chromatography combined with mass spectrometry (LC-MS) analysis has been successfully employed in proteome research. Data generated from LC-MS equipments usually comes with a considerable amount of noise. Thus, there is a need for the use of filters to enhance the quality of mass spectrometry chromatograms. An algorithm developed recently (CODA[2]) achieves good results in removing noise...
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تاریخ انتشار 2013